How GATA2 Deficiency Affects Children’s Development and Disease?

Step by step

1

Centralize GATA2 Deficiency Registry

Generate an European GATA2 genotype-phenotype database

2

Decipher

OMICs data

Genome/transcriptome architecture

Bone marrow microenvironment

Malignancy development

3

Contextualize

Patients perspectives and needs

4

Upgrade

Integrate personalized therapy and follow-up into patient care

The Project Mission


The 3D-GATA2 project mission is to unravel the mechanisms of malignant progression of GATA2 deficiency by combining a European centralised registry with multi-OMICs approaches and in vitro and in vivo modelling. This crucial data will be combined with patient perspectives with the aim of personalising therapy and patient care.


Latest News

The 3D-GATA2 project consortium gathered during the EHA 2025 Congress for a key review meeting marking the first […]
3D-GATA2: Year 1 at EHA 2025
GATA-2 Team
June 24, 2025
The latest publication, authored by consortium partners Marlène Pasquet, Laetitia Largeaud, Camille Hamelle, Eric Delabesse, & Cyril Broccardo, […]
Paper in Blood Cancer Journal
GATA-2 Team
March 25, 2025
The meeting held on 1st of March, 2024, in Toulouse, France, focused on various work packages (WP) related […]
Kickoff meeting
GATA-2 Team
March 2, 2025